Phospho foxo1
WebFOXO1 (Phospho-Ser256) DNA-Binding ELISA Kit. Detection Target: FOXO1 (Phospho-Ser256) Detection Range: 10-30 ug of total protein/well. Quantity: 96 Tests. Supplier Page. Compare Product. WebThe ELISA kits listed below target FOXO1, the symbol for the human gene, forkhead box O1. The protein encoded by FOXO1 has a predicted amino acid length of 655, a mass of 69.7 kDa, and a cytoplasmic and nuclear subcellular localization. Pathologic involvement is reported in Rhabdomyosarcoma 2.
Phospho foxo1
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WebJul 23, 2024 · The FOXO proteins, including FOXO1, FOXO3a, FOXO4, and FOXO6, are implicated in a broad range of cancer-related functions, including cellular differentiation, apoptosis, cell cycle arrest, and... WebPhospho-FoxO1 (Ser256) (E1F7T) recognizes endogenous levels of FoxO1 protein only when phosphorylated at Ser256. The antibody cross-reacts with overexpressed FoxO4 phosphorylated at Ser193 and may cross-react with overexpressed FoxO3a phosphorylated at Ser253. The antibody also cross-reacts with a protein of unknown origin around 160kD.
WebFOXO1 is a regulator of redox balance, osteoblast numbers and controls bone mass. Further, FOXO1 orchestrates the endocrine function of the skeleton in regulating glucose metabolism, and suppresses the … WebHere, we used a system in which Foxo1 transcription-factor activity, which is normally terminated upon cell activation, cannot be silenced, and we show that enforcing Foxo1 activity disrupts homeostasis of CD4 conventional and regulatory T cells.
WebFOXO1 is involved in the insulin regulation of glucose-6-phosphatase (G6p) expression. Additionally, this protein plays a vital role in tumor suppression by inducing growth arrest and apoptosis. Features and Benefits Evaluate our antibodies with complete peace of mind. WebProduct name Anti-FOXO1A (phospho S256) antibody See all FOXO1A primary antibodies Description Rabbit polyclonal to FOXO1A (phospho S256) Host species Rabbit Tested applications Suitable for: WB, IHC-P, ICC/IF more details Species reactivity Reacts with: …
WebFOXO1 is a regulator of redox balance, osteoblast numbers and controls bone mass. Further, FOXO1 orchestrates the endocrine function of the skeleton in regulating glucose metabolism, and suppresses the transcriptional activity of RUNX2, an upstream activator …
WebFeb 25, 2011 · To determine which of the three FoxO1 phosphorylation sites at Thr 24, Ser 256, and Ser 319 are direct targets for PKA-α, we repeated the in vitro immune complex kinase assay represented in Fig. 1 with unlabeled ATP and examined the phosphorylation status of FoxO1 by immunoblotting anti-FLAG immunoprecipitates of transfected HEK293 … norpolfed.orgWebFOXO1 (FKHR or ForkHead in Rhabdomyosarcoma) is a 70 kDa protein. Recent studies have shown that this protein can act as either a coactivator or a corepressor of nuclear receptor activity. This action is mediated through the LXXLL motif found in the C terminus of the FOXO1A protein. norpro canning setWebNov 25, 2015 · # p values of <0.05 indicate significant differences from treatments without UP; (D) The levels of phospho-FOXO1 and phospho-p70S6K1 were measured after treatment with Akt inhibitor by Western blotting. Tubulin was detected as a loading control. norprofilWebFoxo1 is an essential transcription factor required for the survival and differentiation of memory CD8 T cells, yet it is unclear whether these Foxo1-dependent functions are inherently coupled. ... In this study, we show that an S209A phospho-null Foxo1 exhibited Akt-dependent nuclear trafficking in mouse CD8 T cells and augmented the ... nor print any marks upon youWebSeveral transcription factors, including NF-κB, AP-1, and FoxO1, are known to mediate the induction of MMP-9 expression following stimulation by different factors and in various types of cells. 1,25,26,31,32 In our previous study, we also showed that NF-κB and AP-1 contribute to LPS-induced MMP-9 expression in RBA-1 cells. 12,33 Here, we ... norpoint shooting center llcWebMar 27, 2024 · (A) Top: Representative immunoblots of phospho (p)-FOXO1/3a (Thr24/Thr32) and total FOXO1 from NRVM treated with BSA or myristate 500 μM (M500) for 24 h, unstimulated or stimulated with insulin 10 nM for 15 min. β-TUBULIN was used … norpro clip stainless steelhow to remove yahoo search from edge