In the late 1950s and early 1960s, the use of thalidomide in 46 countries by women who were pregnant or who subsequently became pregnant resulted in the "biggest man-made medical disaster ever," with more than 10,000 children born with a range of severe deformities, such as phocomelia, as well as thousands of miscarriages. Krämer-Kornja, Michels and Weinert-Hettmer are three of an estimated 5,000 children in Germanyand 10,000 worldwide who were born with deformities 60 years ago. Their mothers had taken thalidomide, an over-the-counter sleeping pill and sedative produced by German pharmaceutical company Grünenthal. … Zobraziť viac Klaus Michels was born in September 1961. The doctors told his parents that he wouldn't survive, and urged them to "say goodbye now." Today, Michels is 60. Michels attended … Zobraziť viac In May 1962, Gisela Weinert gave birth to her daughter, Claudia. When she asked the doctors whether everything was alright, the doctors gave no answer. Claudia, too, had short arms, and the staff on the maternity ward all … Zobraziť viac Grünenthal paid 100 million German marks($50 million) and the German government paid an additional 100 million into a foundation … Zobraziť viac For many, the recall came too late. Gisela Weinert, Claudia's mother, had no idea how dangerous the tablets were that doctors and pharmacists had recommended, but she still feels … Zobraziť viac
Thalidomide — A Revival Story NEJM
Web1. apr 2004 · Thalidomide was originally used to treat morning sickness, but was banned in the 1960s for causing serious congenital birth defects. Remarkably, thalidomide was … Web1. dec 1996 · CLINICAI REVIEW Rediscovering thalidomide: A review of its mechanism of action, side effects, and potential uses Stephanie Tseng, BA, Grace Pak, MD, Kenneth … touchstone one
Thalidomide remodels developing heart in chick embryo ... - PubMed
Web1. sep 2012 · 2009 Scientists at the University of Aberdeen claim they have solved a "50-year puzzle" after discovering how thalidomide causes limb defects. They found that a component of the drug prevented... WebThe first paper describing the pharmacological actions of thalidomide was published in 1956. The drug, then designated as K17, was thought to have sedative effects superior to … Web16. jan 2024 · Background In the late 1950s and early 1960s the drug Thalidomide was marketed across the world as a non-addictive tranquilizer. Despite being given to … potter\u0027s pasture brady ne